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Twenty-two(88%)of the patients reported frequent loss of balance,and 21 (84%)reported memory loss.Neurologic examination revealed signs of incoordination in 21(84%)of the patients.Neuropsychologic test results showed preservation in certain spheres of functioning,such as verbal IQ, with substantial impairment in others,particularly memory function.On memory tests,70%to 75%showed mild or greater impairment.The majority(17 of 19 tested,or 89%)showed depression on the Minnesota Multiphasic Personality Inventory.The exposure index was significantly correlated with signs and symptoms of incoordination.This study and others in humans and animals support the existence of a syndrome characterized by incoordination,poor memory,impairment in abstract reasoning,and depression.Aluminum exposure in the potroom seems most likely cause. |
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